Mouse genome-wide association mapping needs linkage analysis to avoid false-positive Loci.

A highly significant correlation was found between the spontaneous tumor incidence and urethane-induced tumor multiplicity phenotypes (r = 0.94, −log P = 8.9), whereas correlation between the spontaneous tumor incidence and urethane-induced tumor incidence phenotypes was weaker (r = 0.76, −log P = 3.8) ( Figure 1 ).

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