Thus, in the cortex inactivated by BoNT/E injection, the arbors serving the open eye, which carry visual information, showed a highly significant shrinkage and the shrinkage could be alleviated by visual deprivation, as observed in the cortex inhibited by muscimol treatment [9] , [10] .
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Experience-driven axon retraction in the pharmacologically inactivated visual cortex does not require synaptic transmission.
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