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G-protein coupled receptor signaling architecture of mammalian immune cells.

PLoS One · 2009 · PMC2615211 · PMID 19142232

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practically significantno p-value reported
This question is both scientifically and practically significant because it not only depicts the logic behind the network architecture, but also helps us uncover the potential control points of signaling networks for drug design.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.