Learning to control a brain-machine interface for reaching and grasping by primates.

Thus, during the transition from pole to brain control in task 1, the average correlated firing between pairs of cortical neurons, measured in terms of correlation coefficient (mean ± SEM), increased from 0.02 ± 1 × 10 −4 to 0.06 ± 2 × 10 −4 , a 3-fold rise that was highly significant (Wilcoxon signed rank test, p < 0.0001).

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