Establishing an adjusted p-value threshold to control the family-wide type 1 error in genome wide association studies.

BMC Genomics · 2008 · PMC2621212 · PMID 18976480

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closest p

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highly significantno p-value reported

For the Affymetrix 500 K and Illumina 317 K GWAS SNP panels we recommend using 10 -5 , 10 -7 and 10 -8 and for the Phase II HapMap CEPH Utah and Yoruba populations we recommend using 10 -6 , 10 -7 and 10 -9 as "suggestive", "significant" and "highly significant" p-value thresholds to properly control the family-wide Type 1 error.

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