Methotrexate-induced cutaneous ulceration in patients with erythrodermic mycosis fungoides.

Ther Clin Risk Manag · 2008 · PMC2621414 · PMID 19209294

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may be significantno p-value reported

In patients with toxic serum levels, or possibly with an increased sensitivity to methotrexate, there may be significant necrosis of dividing cells in a particular area of skin, to the point that there are no dividing cells in the basal layer to replace the layers undergoing sloughing.

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