Barely Significant
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Determinants in HIV-1 Nef for enhancement of virus replication and depletion of CD4+ T lymphocytes in human lymphoid tissue ex vivo.

Retrovirology · 2009 · PMC2630989 · PMID 19146681

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highly significantno p-value reported
HIV-1 wt and Δnef served as reference controls and showed the expected and statistically highly significant difference in CD4 + T cell depletion and p24 production.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.