Identification and bioinformatic characterization of a multidrug resistance associated protein (ABCC) gene in Plasmodium berghei.

The bootstrap values for all branches are above 97 percent indicating highly significant support for the clades seen in the gene tree. pbmrp gene organization in drug sensitive and resistant lines To explore whether pbmrp genetic rearrangements and/or an increase in gene copy number contribute to drug resistance in resistant P. berghei lines, Southern blot analysis were performed on restricted gDNA from each of the P. berghei lines (Figure 5 ).

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