Five quantitative trait loci control radiation-induced adenoma multiplicity in Mom1R Apc Min/+ mice.

In addition to the previously reported QTLs on chromosome 16 (p<0.0001; 8), we found two highly significant QTLs (p<0.0001; Table 1 ; Fig. 1 ) on chromosome 5, one significant QTL on chromosome 2, (p<0.0001; Table 1 ; Fig. 1 ) and one suggestive QTL on chromosome 17 for USI trait (p<0.001; Table 1 ).

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The only exception was D2Mit395 (LOD 2.7), which showed borderline significance when analysed using MapManager, but with Cartographer the marker fell just below the significance threshold of LOD 2.8.

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