Inhibition of the norepinephrine transporter improves behavioral flexibility in rats and monkeys.

The latency to initiate a trial and the pellet retrieval time were not altered by GBR [dose × testing condition: all F ’s < 1; dose, respectively: F (1,22) = 1.2, p = 0.31, F (1,22) = 1.3, p = 0.75] (Table 1 ). In terms of the effect of GBR on the accuracy in the first 20 trials of the retention session, the ANOVA failed to reach significance [dose × bin: F (1,22) = 0.1, p = 0.99; dose: F (1,22) = 2.1, p = 0.13] (Fig. 4 b).

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