A new 500 kb haplotype associated with high CD8+ T-lymphocyte numbers predicts a less severe expression of hereditary hemochromatosis.

BMC Med Genet · 2008 · PMC2636778 · PMID 18990219

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highly significantno p-value reported

[ 24 ] that showed by an extended linkage disequilibrium analysis in the hemochromatosis gene region, two distinct peaks of association, namely a highly significant association at D6S2239, localized in close proximity to HFE (14 kilobases telomeric) and at D6S105 [ 24 ].

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