The glutathione biosynthetic pathway of Plasmodium is essential for mosquito transmission.

PLoS Pathog · 2009 · PMC2636896 · PMID 19229315

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highly significantno p-value reported

The highly significant reduction in parasite GSH levels resulting from disruption of the pbggcs gene caused only a relatively minor effect on the growth rate of intraerythocytic stages.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.