A case-control study of sporadic Creutzfeldt-Jakob disease in Switzerland: analysis of potential risk factors with regard to an increased CJD incidence in the years 2001-2004.

In the year 2001, the annual mortality rate increased significantly to 2.6 per million inhabitants from around 1.4 per million observed during the 1990ies.[ 15 ] Figure 1 shows yearly incidences of reported CJD deaths in Switzerland: between 1988 and 2000, an average of 9 definite and probable CJD deaths according to European criteria (maximum: 11 cases in 2000) were reported annually.[ 16 ] In 2001, 19 deaths were reported, an increasing trend that was sustained in the following years with 18 deaths in 2002, 17 in 2003, 16 in 2004, 10 in 2005, 13 in 2006 and 15 deaths in 2007.

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