highly significantP values < 0.0001
No significant difference existed between the caecal loads of the Δ pegA :: cat and Δ pegA mutants ( P values 0.27 and 0.64 at 1 and 3 days post-inoculation, respectively); however in both cases a highly significant reduction in caecal load was detected for each mutant relative to the parent strain ( P values < 0.0001 at 1 day post-infection), consistent with previous findings.