Beta-defensin-2 protein is a serum biomarker for disease activity in psoriasis and reaches biologically relevant concentrations in lesional skin.

PLoS One · 2009 · PMC2649503 · PMID 19266104

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highly significantno p-value reported

Figure 3 shows that there is a modest but highly significant correlation between copy number and hBD-2 protein concentration in serum.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.