Abnormal growth factor/cytokine network in gastric cancer.

Cancer Microenviron · 2008 · PMC2654359 · PMID 19308687

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highly significantno p-value reported

The combination of three or four pro-inflammatory cytokine polymorphisms affecting IL-1 beta (IL-1B-511T), IL-1 receptor antagonist (IL-1RN*2), TNF alpha (TNF-A-308A) and IL-10 (IL-10 haplotype ATA) results in a highly significant increased risk of development of gastric cancer [ 18 ].

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