In such an analysis, even when the GGAA microsatellites located at less than 5 kb are removed, the analysis remains highly significant indicating that the effects of GGAA microsatellites may not be limited to the first 5 kb upstream of the genes.
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The oncogenic EWS-FLI1 protein binds in vivo GGAA microsatellite sequences with potential transcriptional activation function.
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