Analysis of the precision and sensitivity to change of different approaches to assess cartilage loss by quantitative MRI in a longitudinal multicentre clinical trial in patients with knee osteoarthritis.

Arthritis Res Ther · 2008 · PMC2656228 · PMID 18986534

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0.0620

closest p · 1.2× alpha

0.0620

boldest claim

The sentences

a small trendp = 0.062so close (0.05 < p ≤ 0.1)

At 24 months, a small trend favouring mean thickness was observed in the central condyle (volume: licofelone: -35.1 ± 60.9, naproxen: -46.3 ± 40.0, p = 0.062; mean thickness: licofelone: -0.047 ± 0.096 naproxen: -0.067 ± 0.072, p = 0.040), whereas at 6 and 12 months both methods provided similar findings.

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