Genome-wide association studies are coming for human infectious diseases.

However, in comparison with disorders such as inflammatory bowel disease or macular degeneration, for which the small number of genetic variants detected were shown to confer a highly significant disease risk to carriers [ 17 , 22 ], the study on Kawasaki disease [ 20 ] has not found such a profound effect, hinting that infectious disease may not yield easily to the GWAS approach.

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