Evolution of DNA polymerases: an inactivated polymerase-exonuclease module in Pol epsilon and a chimeric origin of eukaryotic polymerases from two classes of archaeal ancestors.

Biol Direct · 2009 · PMC2669801 · PMID 19296856

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closest p

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highly significantno p-value reported

Specifically, the PSI-BLAST search with C-terminal Zn-finger sequence of the yeast Pol ε (amino acids 2116 to 2199) reveals highly significant similarity to the C-terminal Zn-fingers of many archaeal Pol D sequences (E-value 4e-06 in the second search iteration).

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