a weak trendp = 0.27
When we consider only the 24 rapidly evolving sites, we find a weak trend (p = 0.27) towards enrichment within epitope rich regions (odds ratio: 1.6).
When we consider only the 24 rapidly evolving sites, we find a weak trend (p = 0.27) towards enrichment within epitope rich regions (odds ratio: 1.6).
We also observed a highly significant enrichment overall for APOBEC3 motifs among the rapidly diversifying sites identified using HyPhy, even when stringent precautions were taken to exclude the 15 subjects that had enrichment of G→A mutations within the APOBEC3 motif.