Structure-based ligand design and the promise held for antiprotozoan drug discovery.

J Biol Chem · 2009 · PMC2673241 · PMID 19103598

Europe PMC DOI

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may be significantno p-value reported

Given that some drugs act on multiple targets, then there may be significant benefits to adopting a polypharmacology approach that is the “promiscuous modulation of several molecular targets” ( 43 ).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.