Barely Significant
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Intergenic regions of Borrelia plasmids contain phylogenetically conserved RNA secondary structure motifs.

BMC Genomics · 2009 · PMC2674063 · PMID 19267927

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highly significantno p-value reported
The C 14 -G 47 →A 14 -U 47 substitution is highly significant in that it shows the double mutation, pyrimidine→purine, purine→pyrimidine.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.