Predominant modifier of extreme liver cancer susceptibility in C57BR/cdJ female mice localized to 6 Mb on chromosome 17.

Carcinogenesis · 2009 · PMC2675651 · PMID 19255062

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marginally significantno p-value reported

P -values for males from these same recombinant lines were marginally significant when adjusted for multiple comparisons, suggesting that the same region of chromosome 17 that caused the 3- to 7.5-fold increase in females also caused an increase in liver tumor multiplicity in males.

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