Stochasticity in protein levels drives colinearity of gene order in metabolic operons of Escherichia coli.

PLoS Biol · 2009 · PMC2684527 · PMID 19492041

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a pronounced trendno p-value reported

We find a pronounced trend for genes to appear in operons in the same order as they are needed in metabolism (colinearity).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.