Integrated associations of genotypes with multiple blood biomarkers linked to coronary heart disease risk.

Of these, 140 SNPs indexed differences in HDL- and LDL-cholesterol, triglycerides, C-reactive protein, fibrinogen, factor VII, apolipoproteins AI and B, lipoprotein-associated phospholipase A2, homocysteine or folate, some with large effect sizes and highly significant P -values (e.g. 2.15 standard deviations at P = 9.2 × 10 −140 for F7 rs6046 and FVII levels).

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