Mode of action of abatacept in rheumatoid arthritis patients having failed tumour necrosis factor blockade: a histological, gene expression and dynamic magnetic resonance imaging pilot study.

Ann Rheum Dis · 2009 · PMC2689522 · PMID 18772191

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a decreasing trendno p-value reported

Interestingly, a decreasing trend in receptor activator of nuclear factor kappa B (RANK) and RANK ligand (RANKL) gene expression was seen in association with an increase in osteoprotegerin gene expression ( fig 2A ).

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