Barely Significant
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The timing of the shrew: continuous melatonin treatment maintains youthful rhythmic activity in aging Crocidura russula.

PLoS One · 2009 · PMC2690841 · PMID 19526053

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highly significantno p-value reported
In contrast, in the implanted animals (i) the first noticeable decrease in amplitude of the rhythm was delayed by 3 months and (ii) the 24 h period remained highly significant until death ( Figs 3 , 4 ).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.