Barely Significant
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The neuropeptide PDF acts directly on evening pacemaker neurons to regulate multiple features of circadian behavior.

PLoS Biol · 2009 · PMC2702683 · PMID 19621061

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highly significantno p-value reported
While small changes were observed in some pacemaker neuron clusters (lLNv, LNd, and DN3), high amplitude oscillations were observed in all pacemaker neurons groups in Pdfr mutants, in contrast to the highly significant reduction in morning behavior ( Figure 2 ).

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