Barely Significant
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Cellular contractility requires ubiquitin mediated proteolysis.

PLoS One · 2009 · PMC2705188 · PMID 19597551

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highly significantno p-value reported
Our observation, that contractility requires ongoing ubiquitin mediated proteasomal degradation, is highly significant.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.