It is interesting to note that the VPFC foci showed a slight trend toward greater selectivity to emotion when subjects were instructed to judge the emotionality of musical clips (% signal change, negative, closed: 0.62±0.26 with task vs. 0.52±0.19 without task; open: 0.16±0.31 vs. 0.09±0.03; movie: 0.04±0.15 vs. 0.02±0.01; neutral, closed: 0.43±0.14 vs. 0.42±0.16; open: −0.02±0.08 vs. −0.04±0.1; movie: −0.1±0.1 vs. −0.11±0.08).
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Eyes wide shut: amygdala mediates eyes-closed effect on emotional experience with music.
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