borderline significantp =0.09
Multivariate logistic regression analysis revealed only high plasma tHcy as the independent and significant risk factor for moderate-to-severe WMC [odds ratio (OR; adjusted for age, gender, education level, MMSE score, and hypertension comparing the top tertile - tHcy levels ≥12.9 μmol/L - with the bottom tertile - tHcy levels ≤9.4 μmol/L)=7.35; 95% confidence interval, confidence interval=1.36-39.84; p =0.02], and age as a borderline significant risk factor (OR=1.08, 95% CI=0.99-1.19, p =0.09) in AD patients.