The TGFBR1*6A allele is not associated with susceptibility to colorectal cancer in a Spanish population: a case-control study.

BMC Cancer · 2009 · PMC2708189 · PMID 19538729

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marginally significantno p-value reported

(2005) suggested that the 12 case-control studies of Pasche [ 7 ] had marginally significant heterogeneity when pooled and questioned the association between TGFBR1*6A and increased risk of cancer [ 16 ].

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of borderline significanceno p-value reported

Recent studies suggest that the association of the TGFBR1*6A allele with colon cancer is either weak (OR: 1.2; 95% CI: 1.01–1.43) [ 7 ] or of borderline significance (OR: 1.13; 95% CI: 0.98–1.30) [ 10 ].

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