Screening the same transposon library through BALB/cJ mice similarly revealed significant overrepresentation in the negatively selected population of SPI-2 (27/187) and genes involved in lipopolysaccharide (LPS) biosynthesis (9/187), with an overrepresentation of SPI-1 genes (5/187) that fell marginally short of significance at the 5% level.
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Comprehensive identification of Salmonella enterica serovar typhimurium genes required for infection of BALB/c mice.
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