Integrated analysis of DNA methylation and gene expression reveals specific signaling pathways associated with platinum resistance in ovarian cancer.

BMC Med Genomics · 2009 · PMC2712480 · PMID 19505326

Europe PMC DOI

hedged sentence

—

closest p

—

boldest claim

The sentences

highly significantno p-value reported

In the current study, we observed modest but highly significant upregulation of both DNMT1 and DNMT3B in the cisplatin-resistant Round5 ( i.e ., treated for five drug cycles) A2780 subline (Table 1 ), suggesting that the altered methylation profile in these cells may be associated with increased or altered DNMT activity.

also in 132,142 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.