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pH Modulation of efflux pump activity of multi-drug resistant Escherichia coli: protection during its passage and eventual colonization of the colon.

PLoS One · 2009 · PMC2722724 · PMID 19684858

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extremely significantno p-value reported
The demonstration of pH modulated efflux pump activity is extremely significant for the design of agents that are to serve as efflux pump inhibitors (EPIs).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.