Statistically significant association of the single nucleotide polymorphism (SNP) rs13181 (ERCC2) with predisposition to Squamous Cell Carcinomas of the Head and Neck (SCCHN) and Breast cancer in the north Indian population.

J Exp Clin Cancer Res · 2009 · PMC2724389 · PMID 19615095

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0.0001

closest p · 0.0× alpha

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boldest claim

The sentences

highly significantP < 0.0001actually significant

Correspondingly, the present study on the association of the SNP rs13181 with predisposition to Breast cancer showed a significant to highly significant positive association of greater than 2-folds for the rs13181 homozygous mutant (CC) (OR 4.412, 95% CI 2.413 to 8.068, P < 0.0001), heterozygous (AC) (OR 2.086, 95% CI 1.246 to 3.492, P = 0.0056) and combined mutant (AC + CC) (OR 2.672, 95% CI 1.647 to 4.334, P < 0.0001) genotypes.

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