Mass spectrometry-based serum proteome pattern analysis in molecular diagnostics of early stage breast cancer.

Importantly, these most frequent components of cancer classifiers had very high potency to differentiate control and cancer samples by themselves; the statistical significance of differences obtained in univariant analyses for these three peaks were at the level of p-values from 10 -20 to 10 -14 (they remained highly significant after application of the Bonferroni correction for multiple testing; Table 1 ).

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