( 13 ) was able to detect highly significant associations between the non-synonymous rs6232 (N221D) and rs6235 (S690T) SNPs in the prohormone convertase 1/3 ( PCSK1 ) gene and the risk of obesity by using a staged, comprehensive candidate gene approach.
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Association of variants in the PCSK1 gene with obesity in the EPIC-Norfolk study.
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