Restless legs syndrome: differential diagnosis and management with pramipexole.

Clin Interv Aging · 2009 · PMC2739631 · PMID 19750232

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highly significantno p-value reported

They found a highly significant reduction in VAS score and a significant reduction of PLMS index (the primary outcome measure), and increment of sleep stage 2, sleep efficacy and time in bed on the pramipexole night.

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