We could show for the first time that HMGI-C expression is highly significant for worse outcome in univariate analysis, and we could furthermore demonstrate in multivariate analysis that circulating HMGI-C mRNA is a powerful independent prognostic indicator for overall survival.
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Expression of high-mobility-group-protein HMGI-C mRNA in the peripheral blood is an independent poor prognostic indicator for survival in metastatic breast cancer.
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