Some studies have suggested that microvessel density indicated representative angiogenesis of the tumour and was an independent and highly significant prognostic factor for both node-negative and node-positive patients ( Weidner et al , 1991 ; Gasparini et al , 1994 ; Simpson et al , 1996 ; Heimann et al , 1996 ; Kato et al , 2001 ).
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The combination of angiogenesis and blood vessel invasion as a prognostic indicator in primary breast cancer.
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