Barely Significant
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Twelve weeks of protracted venous infusion of fluorouracil (5-FU) is as effective as 6 months of bolus 5-FU and folinic acid as adjuvant treatment in colorectal cancer.

Br J Cancer · 2003 · PMC2741111 · PMID 12799627

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highly significantno p-value reported
Highly significant reduced incidences of diarrhoea, stomatitis and neutropenia occurred in patients treated with PVI 5-FU compared with 5-FU/FA.

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