Penetrance of colorectal cancer among MLH1/MSH2 carriers participating in the colorectal cancer familial registry in Ontario.

Hered Cancer Clin Pract · 2009 · PMC2744657 · PMID 19698169

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a decreasing trendno p-value reported

The global effect of any MMR mutation on CRC was significant and showed a decreasing trend with age (the HR fell from 10.5 at age 30 to 5.5 at age 70).

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