Although highly significant, the mean difference in DNA methylation level even at the most significant locus (TDGF1_P248_R, NM_003212.1 ) in the combined group was modest (0.75, sd 0.04 in females compared to 0.79, sd 0.04 in males. t = 4.5734, df = 169.39, p = 9.23e–06).
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The relationship of DNA methylation with age, gender and genotype in twins and healthy controls.
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