Barely Significant
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Evolutionary constraints permeate large metabolic networks.

BMC Evol Biol · 2009 · PMC2753571 · PMID 19747381

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closest p · 0.0× alpha
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The sentences

highly significantP < 10 -23actually significant
Together they form a highly significant reaction set (P < 10 -23 for each of the three possible reaction pairs), whose congruence in genomic association is nearly perfect.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.