highly significantP = 0.002
In addition, among patients treated with adjuvant anthracycline-based therapy we found a highly significant association with OS both when included as a continuous (HR 4.19, 95% CI 1.67-10.51, P = 0.002) and as a dichotomized variable (HR 2.59, 95% CI 1.14-5.88, P = 0.02).