A decreasing trend was observed in plasmacytoid DC levels with increasing stage, and this was statistically significant for stage II (p = 0.03, n = 8) and stage III (p = 0.004, n = 12) cancers.
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The sentences
Consistent with this observation, intratumoral NK cells display a highly significant decreased expression of activating receptors such as NKG2D, NKp30, NKp80, DNAM-1 and CD16.