sTNFR-II and sICAM-1 are associated with acute disease and hepatic inflammation in schistosomiasis japonica.

In the acute schistosomiasis group, highly significant positive correlations were found between eosinophil count and infection intensity (Pearson correlation = 0.477; P = 0.0072), and eosinophil count and the level of sICAM-1 (Pearson correlation = 0.363; P = 0.0014). 3.3 Immunoglobulin levels in the different clinically defined disease groups ANOVA post hoc tests showed all SEA- and SWAP-specific total IgG and SEA-specific IgG4 levels were significantly higher in the acute, chronic and advanced groups compared with controls ( Fig. 2 ).

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