Overestimation of alternative splicing caused by variable probe characteristics in exon arrays.

Comparing the probeset response slopes predicted by our model with the slopes obtained from the Affymetrix tissue panel data, we detected a highly significant correlation both in mouse and human (Pearson correlation coefficient in mouse 0.528, P << 2.2 × 10 −16 , and in human 0.468, P << 2.2 × 10 −16 ).

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